Episode Description:
CKD often leads to metabolic acidosis due to impaired kidney function, which affects the body’s acid-base balance. Sodium bicarbonate, an alkalinizing agent, helps neutralize excess acid, restoring normal pH levels and reducing kidney strain. This correction is vital for slowing CKD progression, reducing inflammation and fibrosis in the kidneys, and improving nutritional status and muscle function. It also helps preserve bone health by mitigating bone demineralization associated with acidosis.
Despite its benefits, sodium bicarbonate must be used cautiously. Potential risks include sodium overload, which can worsen hypertension and heart failure, and the risk of metabolic alkalosis if overcorrected. It can also interact with other medications, affecting their efficacy.
The application of sodium bicarbonate in CKD treatment should be personalized, starting with a low dose and adjusting based on regular monitoring of serum bicarbonate levels, kidney function, and patient response. The goal is to maintain serum bicarbonate within a normal range, avoiding extremes.
Renes Care Radio is a podcast designed for nephrology professionals, offering in-depth scientific explorations of key topics. It equips kidney care providers with the essential knowledge needed for advanced patient care.
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This podcast is for informational purposes only and is not intended to replace professional medical advice, diagnosis, or treatment.